See exclusive offer for first-time customers! Required fields are marked *. The average … Vitamin deficiency anemia - Symptoms and causes - Mayo Clinic In fact, a 3 oz. View Terms & Privacy. Relieves Stress. Symptoms of deficiency are similar to other vitamin B deficiencies. Skin conditions exist when a body is Vitamin B5 deficient. You should know, though, that B5 deficiency is rare, but it can happen. Symptoms of vitamin B12 deficiency. A deficiency of B5 is very uncommon. Dietary Reference Intakes (DRIs): Recommended Intakes for Individuals, Vitamins. Reply HELP for help and STOP to cancel. Learn More: 11. https://www.ncbi.nlm.nih.gov/books/NBK114311/ †These statements have not been evaluated by the Food and Drug Administration. And when it does you might feel some of the following symptoms – How can you tell if you’re vitamin B5 … Dietary and nutraceutical options for managing the hypertriglyceridemic patient. Vitamin B5 can be destroyed during the cooking process, so try to use fresh produce and steam or grill your meals to help preserve the vitamin content. Fresh meats, vegetables, and whole unprocessed grains have more vitamin B5 than refined, canned, and frozen food. 15. http://lpi.oregonstate.edu/mic/vitamins/pantothenic-acid, Your email address will not be published. 2001;53(5):393-398. Gundry MD Reviews. 3. http://www.umm.edu/health/medical/altmed/supplement/vitamin-b5-pantothenic-acid There is little danger of Vitamin B5 toxicity when it is taken orally. In fact, a recent study shows B5 can significantly lower your total cholesterol and, more importantly, your LDL (or bad cholesterol).8, – Another wonderful use for Vitamin B5 may be to support the healing of wounds and injuries … especially after a surgical procedure. All B vitamins help the body convert food (carbohydrates) into fuel (glucose), which the body uses to produce energy. Want to know what others thought about Gundry MD products? So, there’s a lot to choose from. Consent is not a condition of any purchase. Vitamin B5 is important for wound healing. Some of these studies show that pantethine helped lower LDL (bad) cholesterol and raise HDL (good) cholesterol. All B vitamins are water-soluble, meaning that the body does not store them. Unlike other vitamins, vitamin B5 has no Recommended Dietary Allowance. Therefore prevention of Vitamin B5 Deficiency is as important as treatment. Vitamin B5 contributes to sugar metabolism, so its deficiency causes increased sensitivity of tissue cells to blood sugar levels. 2001;56(3):314-317. Symptoms of deficiency, such as insomnia, leg cramps, or burning feet, have only occurred in experimental situations. B complex vitamins are needed for healthy skin, hair, eyes, and liver. 4. https://ods.od.nih.gov/factsheets/Riboflavin-HealthProfessional/ Because of the potential for side effects and interactions with medications, you should take dietary supplements only under the supervision of a knowledgeable health care provider. Vitamin B5 deficiency is not likely to occur as long as people eat ordinary diets that consist of a variety of foods. Pantothenic acid (also known as vitamin B5) is an essential nutrient that is naturally present in some foods, added to others, and available as a dietary supplement. First-Time Customer? 13. http://lpi.oregonstate.edu/mic/vitamins/pantothenic-acid The deficiency symptoms of Vitamin B5 (Pantothenic Acid) include fatigue, burning feet, depression, insomnia, irritability, muscle cramps, stomach pains, upper respiratory infections and sometimes vomiting. Final Thoughts. 2007 Feb 21; [Epub ahead of print], New York Eye and Ear Infirmary of Mount Sinai, The Blavatnik Family – Chelsea Medical Center, Heart - Cardiology and Cardiovascular Surgery, Supplements with similar uses as: Vitamin B5 (Pantothenic acid), Mount Sinai – Sema4 Health Discovery Initiative Patient Opt Out Registry. A deficiency of vitamin B5 is generally related to having low energy symptoms due to its role in energy production in the body. It is a cause of rheumatoid arthropathy There is heart failure and peripheral neuropathy Similar, neurological in origin, effects include headaches, muscle cramps, and numbness. Naturally occurring vitamin B5 deficiency in humans is very rare and has been observed only in cases of severe malnutrition (20) . These B vitamins are famous. Ellinger S, Stehle P. Efficacy of vitamin supplementation in situations with wound healing disorders: results from clinical intervention studies. – Duck is delicious and a surprisingly good source of B5. Drugs to treat Alzheimer's disease -- Vitamin B5 may increase the effects of a group of drugs called cholinesterase inhibitors, which are used to treat Alzheimer's disease. Vitamin B5 deficiency is rare, but may include symptoms such as fatigue, insomnia, depression, irritability, vomiting, stomach pains, burning feet, and upper respiratory infections. Naturally occurring vitamin B5 deficiency in humans is very rare and has been observed only in cases of severe malnutrition .Pantothenic acid deficiency occurs not isolated but together with other B vitamin … Turns out, B5 might also be a component that can help accelerate the regular healing process by increasing cellular multiplication after surgery.9. Vitamin B5 Deficiency and The Fatigue Factor One of the rarest forms of vitamin deficiency is that involving low levels of Pantothenic acid, or vitamin B5. See our exclusive offer for first-time customers! Naruta E, Buko V. Hypolipidemic effect of pantothenic acid derivatives in mice with hypothalamic obesity induced by aurothioglucose. Scheurig AC, Thorand B, Fischer B, Heier M, Koenig W. Association between the intake of vitamins and trace elements from supplements and C-reactive protein: results of the MONICA/KORA Augsburg study. 6. https://www.ncbi.nlm.nih.gov/books/NBK114311/ However, the vitamin B5 in foods is lost during processing. The information provided herein is intended for your general knowledge only and is not intended to be, nor is it, medical advice or a substitute for medical advice. Save my name, email, and website in this browser for the next time I comment. The best sources are brewer's yeast, corn, cauliflower, kale, broccoli, tomatoes, avocado, legumes, lentils, egg yolks, beef (especially organ meats such as liver and kidney), turkey, duck, chicken, milk, split peas, peanuts, soybeans, sweet potatoes, sunflower seeds, whole-grain breads and cereals, lobster, wheat germ, and salmon. Med Hypotheses. Msg frequency varies. 7 Vitamin B5 deficiency What are the symptoms of vitamin B5 deficiency? B vitamins are vital in terms of keeping your hair, liver, eyes, nervous system, and skin healthy, B5 helps your adrenal glands create the right amount of sex and stress-related hormones, Another responsibility of B5 is to help with red blood cell production, Prebiotic Foods 101 (and the 5 best to eat), The Mediterranean “Longevity” Diet: Why It Works, The Benefits of Taking Biotin Supplements (it’s known as a beauty booster! When folks talk about vitamin B, they’re really talking about eight different B vitamins in total. Nausea is often a related symptom of these signs. That might lead to severe side effects. ), 10 Vitamin D Deficiency Symptoms You Can Identify, The Importance Of Heart Health: Reasons To Keep Your Heart Healthy, Dr. Gundry’s Citrus Fennel “Winter Salad” Recipe. Currently, the possible effects of taking vitamin B5 supplements and royal jelly supplements at the same time are not known. Vitamin B5 has the reputation of reducing stress and other serious mental … The Benefits of Getting Your Vitamin B5 14. http://lpi.oregonstate.edu/mic/vitamins/pantothenic-acid The following could be signs that your Vitamin B5 levels are low – Fatigue; Inability to sleep; Mood Swings; Vomiting; Stomach discomfort; Numbness 6; So, if you start to notice any of the signs above, it might be a good time to check in with your family doctor. 2. http://www.umm.edu/health/medical/altmed/supplement/vitamin-b5-pantothenic-acid For instance, it helps your body process riboflavin (also called vitamin B2).3 And, for the record, riboflavin plays a big part in the production of energy, maintaining proper cellular function and growth, and in the metabolism of fats.4, Another helpful aspect of B5 is that it can help synthesize cholesterol.5 You might be wondering what the word synthesize even means…. Vitamin B5 deficiency is extremely rare in people as pantothenic acid is found in … 2008;66(1-2):1-14. - Vitamin B (thiamine): Deficiencies trigger depression and irritability and can cause neurological and cardiac disorders among alcoholics. Deficiency. This product is not intended to diagnose, treat, cure or prevent any disease. Vitamin B12, also called cobalamin, helps regulate the nervous system.It also plays a role in growth and red blood cell formation. Larger studies are needed to see whether pantethine has any real benefit. All Rights Reserved In fact, just ½ of a California avocado can give you 1 mg of B5.12 And I suggest eating an avocado every single day, in fact, check out this delicious recipe: – Mushrooms are not only tasty, but they’re a great meat substitute for anyone who prefers a vegetarian or vegan lifestyle. Vitamin B5 Deficiency The RDA for vitamin B5 is 5 mg for both men and women with an estimated safe and adequate daily intake for adults between 4 and 7 mg. If you are being treated with any of the following medications, you should not use vitamin B5 supplements without first talking to your health care provider. So with cholesterol, your body starts out with different enzymes and mixes them together to form cholesterol. More studies are needed to confirm these findings. Pregnant and breastfeeding women should not exceed the daily adequate intake unless directed by their doctor. Vitamin B12, also called cobalamin, helps regulate the nervous system.It also plays a role in growth and red blood cell formation. Other studies, mostly in test tubes and animals but a few on people, suggest that vitamin B5 supplements may speed wound healing, especially following surgery. 2009 Nov;12(6):588-95. Review. If you do start to mind your B5 intake, you’ll find there are several potential benefits. Signs may vary but may include, changes in … Joncyzk R, Ronconi S, Rychlik M, Genschel U. Pantothenate synthetase is essential but not limiting for pantothenate biosynthesis in Arabidopsis. Another responsibility of B5 is to help with red blood cell production.7. So, the next time you’re fixing dinner and thinking about how to get a little more B5 on your plate, start with the foods listed here. Now that you know all that B5 can do for you, don’t you want to know the best sources of B5? Your body needs pantothenic acid to synthesize cholesterol. The two separate ingredients become one white, fluffy meringue. So, if you start to notice any of the signs above, it might be a good time to check in with your family doctor. Gundry MD © 2021. Philadelphia, PA: Saunders, An Imprint of Elsevier. 2006 Jan-Feb;89(1):285-8. Now, all B vitamins – including B5 – are water-soluble. Lethargy and irritability, accompanied by … Vitamin B5 is also important in maintaining a healthy digestive tract, and it helps the body use other vitamins, particularly B2 (also called riboflavin). 12. http://lpi.oregonstate.edu/mic/vitamins/pantothenic-acid Vitamin B5, also called pantothenic acid, is one of 8 B vitamins. You should know, though, that B5 deficiency is rare, but it can happen. Well, B vitamins help your body transform the food you eat – mainly carbs – into the fuel your body needs – aka glucose. It is available in a variety of forms including tablets, softgels, and capsules. The nervous system can be greatly affected by a Vitamin B5 deficiency. 10. http://www.duckhealth.com/foodvalu.html Just a 3.5 oz serving of duck yields a little over 1.5 mg of pantothenic acid.10, And considering the recommended daily dose of B5 is 5 mg, with duck for dinner, you’re well on your way to meeting your body’s requirement.11. Your Smart Food Choices, Quinoa Lectins: Why Quinoa Is NOT Part Of A Healthy Diet, Everything You Need To Know About Lectin Toxicity. It’s not common to have a B5 deficiency… Flavonoids Polyphenols: What Are Flavonoids And What They Do? 2011. – Avocados are one of the healthiest foods you can put in your stomach. The Beneficial Effects Of Resveratrol Quercetin, A Quick Lectin free Cereal Recipe For Your Breakfast, Everything You Need To Know About Polyphenols In Coffee, Black Tea Polyphenols Vs Green Tea Polyphenols, Which Plant Foods Have Lectins? Vitamin B5 foods are not hard to find or expensive. Use only as directed. Supplements Turns out, pantothenic acid (B5) is actually named after the Greek word “pantothen” – this means from everywhere. It is sometimes called the "anti-stress" vitamin, but there is no concrete evidence whether it helps the body withstand stress. Hence, the lack of it can decrease the metabolism of proteins, fats, and carbohydrates leading to underlying deficiency syndromes. Symptoms of a B5 deficiency are likely to include: headache fatigue irritability impaired muscle coordination gastrointestinal problems Furthermore, B5 helps you synthesize hormones in your adrenal gland. The main function of this water-soluble B vitamin … Consult your healthcare provider before using supplements or providing supplements to children under the age of 18. This new substance can then be put to good use as one of the main building blocks for most of your cell membranes. In: Kastrup EK, Hines Burnham T, Short RM, et al, eds. Not only are they good for you, they can all be the star of your savory dinner. It’s an entirely new substance made from different original pieces. Vitamin B5 deficiency is rare, but may include symptoms such as fatigue, insomnia, depression, irritability, vomiting, stomach pains, burning feet, and upper respiratory infections. Vitamin B5 deficiency is a somewhat controversial topic. Plant Mol Biol. The Mediterranean “Longevity” Diet: Why It Works, Sources This may be particularly true if vitamin B5 is combined with vitamin C. Preliminary evidence suggests that pantothenic acid might improve symptoms of rheumatoid arthritis (RA), but the evidence is weak. It’s sort of like cooking or baking… you take two parts – like egg whites and sugar – and mix (or synthesize) them together. Basically, it’s the process of fusing together different pieces to make a new whole. A rare vitamin B5 deficiency … You should not take these drugs with B5 unless under a doctor's supervision. Very high doses may cause diarrhoea and may potentially increase the risk of bleeding. Causes of Vitamin B5 Deficiency It is very rare for a naturally occurring vitamin B5 deficiency to be recorded in humans and has only been observed in cases of acute malnutri… Your email address will not be published. 8. https://www.ncbi.nlm.nih.gov/pubmed/21925346 Other studies show that calcium pantothenate improves symptoms of RA, including morning stiffness and pain. Taking any one of the B vitamins for a long period of time can result in an imbalance of other important B vitamins. – There are a number of ways in which vitamin B5 can help you maintain a good level of energy. Vitamin B5, more commonly known as pantothenic acid, is a water-soluble nutrient that is part of the B vitamin family. 5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772032/ Vitamin B5 deficiency: The 99p seeds to eat to top up levels of this essential vitamin VITAMIN B5 is a water-soluble vitamin and is also known as pantothenic acid. They include vitamins B1, B2, B3, B5, B6, B7, B9, and B12. It is also important for high cholesterol lowering. And while B5 plays an important role in breaking down fats and carbohydrates for energy, it’s also a massive helper to your body in the making of red blood cells. Terms & Conditions | Privacy Policy. Accessed June 1, 2011. All vitamin B complex supplements act in this way and should be taken at different times from tetracycline. Msg & data rates may apply. Henry's Clinical Diagnosis and Management by Laboratory Methods, 22nd ed. Causes. Vitamin B5 and Health Because pantothenic acid helps to break down fats, it has been studied for a potential role in reducing cholesterol levels in people who have dyslipidemia. While all of these B vitamins have a lot in common, there are also some major differences between them. It helps … And when it does you might feel some of the following symptoms –, The following could be signs that your Vitamin B5 levels are low –. Pantothenic acid gets its name from the Greek root pantos, meaning "everywhere," because it is available in a wide variety of foods. Very high doses may cause diarrhea and may increase the risk of bleeding. Check out Bio Complete 3 reviews, PrebioThrive reviews, and Total Restore reviews. While there are several different kinds of vitamin B, if you can remind yourself to make a little room in your diet for vitamin B5, you’ll be one big step closer to a healthier body. St. Louis, Mo: Facts and Comparisons; 2000:4-5. Water-soluble vitamins. But not all studies agree. Nutrients and Nutritional Agents. lack of it can decrease the metabolism of proteins, fats, and carbohydrates leading to underlying deficiency syndromes. A derivative of pantothenic acid called pantethine is being studied to see if it may help lower cholesterol levels in the body. If you suffer from eating disorders or have substance abuse issues, however, vitamin B5 deficiency … JAOAC Int. Your body then uses that glucose to produce the energy it needs to carry out a bunch of the functions that keep you alive. Pantothenic acid (Vitamin B5) is a water-soluble vitamin and as such, it is unlikely to reach toxic levels. This causes a drop in blood sugar levels … In addition to playing a role in the breakdown of fats and carbohydrates for energy, vitamin B5 is critical to the manufacture of red blood cells, as well as sex and stress-related hormones produced in the adrenal glands, small glands that sit atop the kidneys. 1. http://www.umm.edu/health/medical/altmed/supplement/vitamin-b5-pantothenic-acid cart reminders) from Gundry MD at the cell number used when signing up. Sign up for the newsletter, and let Dr. Gundry make healthy living simple for you! Vitamin B5 Deficiency and The Fatigue Factor One of the rarest forms of vitamin deficiency is that involving low levels of Pantothenic acid, or vitamin B5. That means your body can’t store them long-term, and you need to get them from outside sources – like food. The goal of Vitamin B5 Deficiency treatment is the prevention of peripheral neuropathy and heart failure. Pins JJ, Keenan JM. Inhibition of acetyl-CoA carboxylase by cystamine may mediate the hypotriglyceridemic activity of pantethine. These B vitamins, often referred to as B complex vitamins, also help the body use fats and protein. Exp Toxicol Pathol. Pantothenic acid deficiency occurs not isolated but together with other B vitamin deficiencies. We've revised our Privacy Policy pursuant to GDPR.Please take a moment to review. Vitamin B5 Benefits & How To Tell if You’re Deficient. So today, let’s talk about vitamin B5 – also known as pantothenic acid. There’s more really good news about B5. They’re commonly called the B-complex vitamins, and they’re really helpful when it comes breaking down, using, and storing fats and proteins. In some open studies, pantethine seems to lower levels of cholesterol and triglycerides in people with diabetes. Curr Opin Clin Nutr Metab Care. All of these functions help raise your energy level and keep your body operating in a healthy way. Consumption of vitamin B5 foods on a consistent basis is the safest way to ensure proper B5 levels. Symptoms include fatigue and general weakness. And it may seem like there’s a ton to remember when it comes to how to keep yourself – and your family – healthy. – Vitamin B5 is also a potential aid when it comes to supporting a healthier cholesterol profile. Severe deficiency can cause numbness and burning of the hands and feet, headache, extreme tiredness, irritability, restlessness, sleeping problems, stomach pain, … Antibiotics, Tetracycline -- Vitamin B5 interferes with the absorption and effectiveness of the antibiotic tetracycline. Vitamin B5 deficiency is very rare. Vitamin B5 … Deficiency. Cholinesterase inhibitors include: Since high doses of vitamin B5 can increase bleeding, you should take extra care if you take blood-thinning medications, such as warfarin (Coumadin), aspirin, and others. One study found that people with RA may have lower levels of B5 in their blood than healthy people, and the lowest levels were associated with the most severe symptoms. Vitamin B5 is available as a supplement in a few forms, including D-pantothenic acid as well as calcium pantothenate and dexpanthenol, which are chemically derived from D-pantothenic acid. People searching for this on the Internet will find many articles that are usually linked to sales sites that suggest routine deficiency of this vitamin, causing conditions that range from acne to depression and so on. 9. http://europepmc.org/abstract/med/3243694 Food While low amounts of this vitamin are occasionally noted, it should be mentioned that true vitamin B5 deficiency … McPherson. 7. http://www.umm.edu/health/medical/altmed/supplement/vitamin-b5-pantothenic-acid The B Vitamin B5 (pantothenic acid) occurs to some extent in all foods however the richest source are: brewers yeast, organ meats (liver, kidney, heart, brain), eggs, milk, vegetables, legumes and … … National Academy of Sciences. Severe deficiency can cause numbness and burning of the hands and feet, headache, extreme tiredness, irritability, restlessness, sleeping problems, stomach pain, heartburn, diarrhea, nausea, vomiting, and loss of appetite. Prebiotic Foods 101 (and the 5 best to eat) Not only that, but B5 helps your adrenal glands create the right amount of sex and stress-related hormones.2. If you have or suspect you have a specific medical condition or disease, please consult your healthcare provider. Like other B complexes, vitamin B5 is also essential for providing energy to the body for carrying out various bodily functions. A vitamin B12 deficiency … For this reason, you may want to take a B complex vitamin, which includes all the B vitamins. The deficiency symptoms of Vitamin B5 (Pantothenic Acid) include fatigue, burning feet, depression, insomnia, irritability, muscle cramps, stomach pains, upper respiratory … Symptoms of vitamin B5 deficiency are fatigue, chronic stress, and depression. It’s incredibly rare for someone to get a B5 deficiency… Vitamin B5 is needed for hormone formation and the uptake of amino acids and the brain chemical acetylcholine, which combine to prevent certain types of depression. Symptoms of vitamin B12 deficiency. Even then, severe symptoms have occurred only if people also take a drug that interferes with the vitamin. They also help the nervous system function properly. Several small, double-blind studies suggest that pantethine may help reduce triglycerides, or fats, in the blood in people who have high cholesterol. Skincare It’s a name that refers to the presence of B5 in a large variety of foods. If you suffer from eating disorders or have substance abuse issues, however, vitamin B5 deficiency can pose a real threat to your health and lead to debilitating fatigue. Often, other B-complex vitamins such as vitamin B6 or B12 get much more attention as compared to vitamin B5 but this doesn’t make it less important for the body. Your diet, too they include vitamins B1, B2, B3, B5, called. Separately under the age of 18 little danger of vitamin B5 can help accelerate regular... Kastrup EK, Hines Burnham t, Short RM, et al eds! Levels in the body for carrying out various bodily functions anti-stress '' vitamin, it... Supplements act in this way and should be taken with water, preferably eating! In terms of keeping your hair, eyes, and total Restore reviews ability to help red... To carry out a bunch of the B vitamins GDPR.Please take a Drug that interferes with the absorption effectiveness. That consist of a variety of forms including tablets, softgels, and let Dr. Gundry make healthy simple! Whether it helps the body does not store them healthier cholesterol profile furthermore, B5 helps you hormones! Someone to get a B5 deficiency… a deficiency of B5 in a variety...: Kastrup EK, Hines Burnham t, Short vitamin b5 deficiency, et al, eds neurological... Your stomach only are they good for you, don ’ t store them long-term and! Way to ensure proper B5 levels different B vitamins help the body mediate! Increasing cellular multiplication after surgery.9 taking any one of the functions that you... To make a new whole State University, it ’ s a lot common. Lot in common, there ’ s more really good news about B5 times from tetracycline s the of., it has only vitamin b5 deficiency found in multivitamins and B complex vitamins, or burning feet is a sign vitamin! B5 Deficient your diet, too today, let ’ s the of... Can result in an imbalance of other important B vitamins, vitamin B5 lends a hand to other in! But together with other B vitamin deficiencies your diet, too may diarrhea... Right amount of sex and stress-related hormones.2 diarrhea and may increase the risk of bleeding been evaluated by food... Fluffy meringue delicious and a surprisingly good source of B5 is very.... Have only occurred in experimental situations How to Tell if you ’ re Deficient and as,..., nervous system, and website in this way and should be taken with,! Re Deficient for pantothenate biosynthesis in Arabidopsis the right amount of sex and stress-related hormones.2 Facts and ;... Doctors consider vitamin B5 is needed for hormone formation and the uptake of amino and... How to Tell if you ’ re really talking about eight different B vitamins very uncommon take vitamins!, vitamin B5 is very uncommon carbohydrates leading to underlying deficiency syndromes vitamins for a long period time. Covid-19, click here is unlikely to reach toxic levels them long-term, and carbohydrates to. Amino acids and the uptake of amino acids and the uptake of amino acids the. It helps the body withstand Stress stress-related hormones.2 used when signing up via text, you agree to receive automated... By their doctor imbalance of other important B vitamins reviews, PrebioThrive reviews, and skin healthy.1 savory.! Choose from t you want to take a moment to Review dietary.! Are not known suggests that vitamin B5 foods on a consistent basis is the prevention of B5... An entirely new substance made from different original pieces B5 benefits & How Tell. By the food you eat into chemical energy deficiency treatment is the safest way to ensure B5. Substance can then be put to good use as one of the tetracycline! ( 6 ):588-95. Review vitamin deficiencies under a doctor 's supervision interferes with the absorption and effectiveness the! If it may help lower cholesterol levels in the body withstand vitamin b5 deficiency by … the goal of B5! Improves symptoms of vitamin B5 foods are not known potential aid when it is unlikely to toxic. But B5 helps your adrenal gland is to help convert the food and Drug Administration you! Disorders among alcoholics larger studies are needed for hormone formation and the brain chemical … Stress... Policy pursuant to GDPR.Please take a B complex vitamin, which could cause symptoms of RA, morning... Levels of cholesterol and raise HDL ( good ) cholesterol mixes them together to form cholesterol body withstand Stress are. White, fluffy meringue before using supplements or providing supplements to children under the names pantothenic acid called is... Is to help with red blood cell production.7 acid deficiency occurs not but. And vitamin B5 deficiency What are flavonoids and What they do website this!